[Ag(bpy)(PPhtBu2)(OCF3)]: a stable nucleophilic reagent for chemoselective and stereospecific trifluoromethoxylation of secondary alkyl nosylates. Issue 11 (24th April 2019)

• Record Type: Journal Article
• Authors: Chen, Daoqian; Lu, Long; Shen, Qilong
• Is Part Of: Organic chemistry frontiers. Volume 6:Issue 11(2019)
• Page Start: 1801
• Page End: 1806
• Publication Date: 2019-04-24
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/c9qo00278b
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : The development of a thermally stable and light-insensitive nucleophilic trifluoromethoxylative reagent [Ag(bpy)(PPh t Bu2 )(OCF3 )]2, which was synthesized in high yields via a three-step one-pot process from easily available trifluoromethyl triflate (TFMT) and AgF at room temperature, is described. Abstract : The development of a thermally stable and light-insensitive nucleophilic trifluoromethoxylative reagent [Ag(bpy)(PPh t Bu2 )(OCF3 )]2, which was synthesized in high yields via a three-step one-pot process from easily available trifluoromethyl triflate (TFMT) and AgF at room temperature, is described. The high reactivity of reagent2 was demonstrated by its high yielding chemoselective and stereospecific SN 2-type trifluoromethoxylation with secondary alkyl nosylates.