A Rare Cause of Diffuse Parenchymal Lung Disease together with Granulomatous Reaction: Pulmonary Amyloidosis. (28th February 2013)

• Record Type: Journal Article
• Authors: Ozer Simsek, Zuhal; Oymak, Fatma Sema; Tutar, Nuri; Canoz, Ozlem; Demir, Ramazan
• Other Names: Aspa F. J. Academic Editor.; Gabbay E. Academic Editor.; Majid A. Academic Editor.; Nakayama K. Academic Editor.
• Is Part Of: Case reports in pulmonology. Volume 2013(2013)
• Publication Date: 2013-02-28
• Subjects: Lungs -- Diseases -- Periodicals; Respiratory organs -- Diseases -- Periodicals; Respiratory infections -- Periodicals; Lung Diseases; Respiratory Tract Diseases; Respiratory Tract Infections; Lungs -- Diseases; Respiratory infections; Respiratory organs -- Diseases; Periodicals; Case Reports; Electronic journals; Periodicals; 616.2
• DOI: 10.1155/2013/837190
• Languages: English
• ISSNs: 2090-6846

Abstract

Abstract : Amyloidosis is a heterogeneous group of disorder associated with the deposition of protein in an abnormal fibrillar form. Primary Sjögren's syndrome (PSS) is a systemic inflammatory disorder that commonly affects the exocrine glands. The reported frequency of pulmonary involvement in PSS varies widely, ranging from 9% to 75%. Pulmonary involvement occurs in light-chain (AL) amyloidosis and is uncommon in the reactive (AA) and hereditary forms. Herein we present a case of PSS associated diffuse multinodular amyloidosis in the lung. We followed up the patient without treatment for three years. There are only minimal lung symptoms related to lung infiltration. In conclusion, pulmonary involvement in SS is an extremely rare clinical manifestation and usually has a good survival rate without treatment.