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Catalytic Synthesis of Pyrazolo[3, 4-d]pyrimidin-6-ol and Pyrazolo[3, 4-d]pyrimidine-6-thiol Derivatives Using Nanoparticles of NaX Zeolite as Green Catalyst. (4th April 2013)
Record Type:
Journal Article
Title:
Catalytic Synthesis of Pyrazolo[3, 4-d]pyrimidin-6-ol and Pyrazolo[3, 4-d]pyrimidine-6-thiol Derivatives Using Nanoparticles of NaX Zeolite as Green Catalyst. (4th April 2013)
Main Title:
Catalytic Synthesis of Pyrazolo[3, 4-d]pyrimidin-6-ol and Pyrazolo[3, 4-d]pyrimidine-6-thiol Derivatives Using Nanoparticles of NaX Zeolite as Green Catalyst
Abstract : An efficient and environmental benign method is reported for the synthesis of some pyrazolopyrimidine derivatives using 3-methyl-1-phenyl-5-pyrazolone with carbonyl compounds in the presence of nanozeolite Nax catalysts, solvent-free and at reflux conditions. It is noteworthy to mention that this method of the synthesis requires less time, less temperature, and better yield.