Polymyositis-Dermatomyositis and Interstitial Lung Disease in Pregnant Woman Successfully Treated with Cyclosporine and Tapered Steroid Therapy. (11th March 2019)

• Record Type: Journal Article
• Authors: Mayu, Saito; Isojima, Sakiko; Miura, Yoko; Nishimi, Shinichiro; Hatano, Mika; Tokunaga, Takahiro; Takahashi, Ryo; Koide, Keiko; Miwa, Yusuke
• Other Names: Mikdashi Jamal Academic Editor.
• Is Part Of: Case reports in rheumatology. Volume 2019(2019)
• Publication Date: 2019-03-11
• Subjects: Rheumatology -- Periodicals; Rheumatology -- Case studies -- Periodicals; Rheumatic Diseases; Connective Tissue Diseases; Rheumatology; Periodicals; Electronic journals; Case studies; Periodicals; 616.723
• DOI: 10.1155/2019/4914631
• Languages: English
• ISSNs: 2090-6889

Abstract

Abstract : Polymyositis-dermatomyositis is extremely rare during pregnancy, and immunosuppressive therapy should be administered after carefully considering the effects on both the mother and fetus. Several reports have associated the disease activity with fetal prognosis, higher rates of eclampsia, preterm births, and fetal deaths. We report our experience with a patient who was diagnosed with polymyositis-dermatomyositis complicated by interstitial lung disease during pregnancy and was treated with a combination-immunosuppressant regimen. To the best of our knowledge, this is the first case wherein cyclosporine was used concomitantly with a steroid for the treatment of polymyositis diagnosed during pregnancy, with successful outcome of childbirth without any complications.