Sarcoidosis Presenting as Löfgren's Syndrome with Myopathy. (2nd April 2013)

• Record Type: Journal Article
• Authors: Kobak, Şenol; Yalçin, Murat; Sever, Fidan; Oncel, Guray
• Other Names: Bannwarth B. Academic Editor.; Gresser U. Academic Editor.; Tsay G. J. Academic Editor.
• Is Part Of: Case reports in rheumatology. Volume 2013(2013)
• Publication Date: 2013-04-02
• Subjects: Rheumatology -- Periodicals; Rheumatology -- Case studies -- Periodicals; Rheumatic Diseases; Connective Tissue Diseases; Rheumatology; Periodicals; Electronic journals; Case studies; Periodicals; 616.723
• DOI: 10.1155/2013/125251
• Languages: English
• ISSNs: 2090-6889

Abstract

Abstract : A 34-year-old female patient, who had proximal muscle weakness for 8 months, presented with erythema nodosum lesions on the pretibial region in addition to pain, swelling, and movement restriction in both ankles for the last one month. Thoracic CT demonstrated hilar and mediastinal lymphadenopathy. She underwent mediastinoscopic lymph node biopsy; biopsy result was consistent with noncaseating granuloma. Serum angiotensin converting enzyme level and muscle enzymes have been elevated. Muscular MRI and EMG findings were consistent with myositis. Muscle biopsy was done, and myopathy was found. The patient was diagnosed with sarcoidosis, Löfgren's syndrome, and sarcoid myopathy. The patient displayed remarkable clinical and radiological regression after 6-month corticosteroid and MTX therapy.