An Atraumatic Femoral Fracture in a Patient with Rheumatoid Arthritis and Osteoporosis Treated with Denosumab. (5th December 2013)

• Record Type: Journal Article
• Authors: Villiers, J.; Clark, D. W.; Jeswani, T.; Webster, S.; Hepburn, A. L.
• Other Names: Kuwana M. Academic Editor.; Salazar-Paramo M. Academic Editor.
• Is Part Of: Case reports in rheumatology. Volume 2013(2013)
• Publication Date: 2013-12-05
• Subjects: Rheumatology -- Periodicals; Rheumatology -- Case studies -- Periodicals; Rheumatic Diseases; Connective Tissue Diseases; Rheumatology; Periodicals; Electronic journals; Case studies; Periodicals; 616.723
• DOI: 10.1155/2013/249872
• Languages: English
• ISSNs: 2090-6889

Abstract

Abstract : Osteoporosis is responsible for a significant burden both individually and socially, but is readily treated with antiresorptive agents and mineral supplementation. However, long-term usage of these agents, notably bisphosphonates, is rarely associated with atypical fractures. Denosumab is a monoclonal antibody that reduces osteoclast activity and thus increases bone mineral density. In this case report, we present a 78-year-old woman with a background of rheumatoid arthritis and osteoporosis who presented with an atypical diaphyseal femoral fracture.