Colorectal Carcinoma: Local Tumor Staging and Assessment of Lymph Node Metastasis by High-Resolution MR Imaging in Surgical Specimens. (2nd November 2009)

• Record Type: Journal Article
• Authors: Yamada, Ichiro; Yoshino, Norio; Tetsumura, Akemi; Okabe, Satoshi; Enomoto, Masayuki; Sugihara, Kenichi; Kumagai, Jiro; Shibuya, Hitoshi
• Other Names: Wei Guowei Academic Editor.
• Is Part Of: International journal of biomedical imaging. Volume 2009(2009)
• Publication Date: 2009-11-02
• Subjects: Diagnostic imaging -- Periodicals; Imaging systems in medicine -- Periodicals; Imagerie pour le diagnostic; Imagerie médicale; Diagnostic imaging; Imaging systems in medicine; Diagnostic Imaging -- Periodicals; Electronic journals; Periodicals; 616.0754
• DOI: 10.1155/2009/659836
• Languages: English
• ISSNs: 1687-4188

Abstract

Abstract : Purpose . To assess the accuracy of high-resolution MR imaging as a means of evaluating mural invasion and lymph node metastasis by colorectal carcinoma in surgical specimens. Materials and Methods . High-resolution T1-weighted and T2-weighted MR images were obtained in 92 surgical specimens containing 96 colorectal carcinomas. Results . T2-weighted MR images clearly depicted the normal colorectal wall as consisting of seven layers. In 90 (94%) of the 96 carcinomas the depth of mural invasion depicted by MR imaging correlated well with the histopathologic stage. Nodal signal intensity on T2-weighted images (93%) and nodal border contour (93%) were more accurate than nodal size (89%) as indicators of lymph node metastasis, and MR imaging provided the highest accuracy (94%–96%) when they were combined. Conclusion . High-resolution MR imaging is a very accurate method for evaluating both mural invasion and lymph node metastasis by colorectal carcinoma in surgical specimens.