A New Methodology for Multiscale Myocardial Deformation and Strain Analysis Based on Tagging MRI. (29th December 2009)

• Record Type: Journal Article
• Authors: Florack, Luc; van Assen, Hans
• Other Names: Zhao Shan Academic Editor.
• Is Part Of: International journal of biomedical imaging. Volume 2010(2010)
• Publication Date: 2009-12-29
• Subjects: Diagnostic imaging -- Periodicals; Imaging systems in medicine -- Periodicals; Imagerie pour le diagnostic; Imagerie médicale; Diagnostic imaging; Imaging systems in medicine; Diagnostic Imaging -- Periodicals; Electronic journals; Periodicals; 616.0754
• DOI: 10.1155/2010/341242
• Languages: English
• ISSNs: 1687-4188

Abstract

Abstract : Myocardial deformation and strain can be investigated using suitably encoded cine MRI that admits disambiguation of material motion. Practical limitations currently restrict the analysis to in-plane motion in cross-sections of the heart (2D + time), but the proposed method readily generalizes to 3D + time. We propose a new, promising methodology, which departs from a multiscale algorithm that exploits local scale selection so as to obtain a robust estimate for the velocity gradient tensor field. Time evolution of the deformation tensor is governed by a first-order ordinary differential equation, which is completely determined by this velocity gradient tensor field. We solve this matrix-ODE analytically and present results obtained from healthy volunteers as well as from patient data. The proposed method requires only off-the-shelf algorithms and is readily applicable to planar or volumetric tagging MRI sampled on arbitrary coordinate grids.