Implementation and Application of PSF-Based EPI Distortion Correction to High Field Animal Imaging. (24th November 2009)

• Record Type: Journal Article
• Authors: Paul, Dominik; Zaitsev, Maxim; Harsan, Laura; Kurutsch, Anja; Splitthoff, Daniel Nico; Hennel, Franciszek; Choli, Morwan; von Elverfeldt, Dominik
• Other Names: Chen J. C. Academic Editor.
• Is Part Of: International journal of biomedical imaging. Volume 2009(2009)
• Publication Date: 2009-11-24
• Subjects: Diagnostic imaging -- Periodicals; Imaging systems in medicine -- Periodicals; Imagerie pour le diagnostic; Imagerie médicale; Diagnostic imaging; Imaging systems in medicine; Diagnostic Imaging -- Periodicals; Electronic journals; Periodicals; 616.0754
• DOI: 10.1155/2009/946271
• Languages: English
• ISSNs: 1687-4188

Abstract

Abstract : The purpose of this work is to demonstrate the functionality and performance of a PSF-based geometric distortion correction for high-field functional animal EPI. The EPI method was extended to measure the PSF and a postprocessing chain was implemented in Matlab for offline distortion correction. The correction procedure was applied to phantom and in vivo imaging of mice and rats at 9.4T using different SE-EPI and DWI-EPI protocols. Results show the significant improvement in image quality for single- and multishot EPI. Using a reduced FOV in the PSF encoding direction clearly reduced the acquisition time for PSF data by an acceleration factor of 2 or 4, without affecting the correction quality.