Patient Specific Dosimetry Phantoms Using Multichannel LDDMM of the Whole Body. (29th June 2011)

• Record Type: Journal Article
• Authors: Tward, Daniel J.; Ceritoglu, Can; Kolasny, Anthony; Sturgeon, Gregory M.; Segars, W. Paul; Miller, Michael I.; Ratnanather, J. Tilak
• Other Names: Kadah Yasser M. Academic Editor.
• Is Part Of: International journal of biomedical imaging. Volume 2011(2011)
• Publication Date: 2011-06-29
• Subjects: Diagnostic imaging -- Periodicals; Imaging systems in medicine -- Periodicals; Imagerie pour le diagnostic; Imagerie médicale; Diagnostic imaging; Imaging systems in medicine; Diagnostic Imaging -- Periodicals; Electronic journals; Periodicals; 616.0754
• DOI: 10.1155/2011/481064
• Languages: English
• ISSNs: 1687-4188

Abstract

Abstract : This paper describes an automated procedure for creating detailed patient-specific pediatric dosimetry phantoms from a small set of segmented organs in a child's CT scan. The algorithm involves full body mappings from adult template to pediatric images using multichannel large deformation diffeomorphic metric mapping (MC-LDDMM). The parallel implementation and performance of MC-LDDMM for this application is studied here for a sample of 4 pediatric patients, and from 1 to 24 processors. 93.84% of computation time is parallelized, and the efficiency of parallelization remains high until more than 8 processors are used. The performance of the algorithm was validated on a set of 24 male and 18 female pediatric patients. It was found to be accurate typically to within 1-2 voxels (2–4 mm) and robust across this large and variable data set.