Vascular effects of the lercanidipine/enalapril combination: clinical relevance. (30th September 2016)

• Record Type: Journal Article
• Authors: Parati, Gianfranco
• Is Part Of: Current medical research and opinion. Volume 32(2016)Supplement 2
• Page Start: 25
• Page End: 28
• Publication Date: 2016-09-30
• Subjects: Hypertension -- Lercanidipine -- Microcirculation -- Stiffness -- Vascular effects; Clinical medicine -- Periodicals; Therapeutics -- Periodicals; 615.5
• DOI: 10.1080/03007995.2016.1218837
• Languages: English
• ISSNs: 0300-7995

Abstract

Abstract: Hypertension is associated with alterations in the vascular structure, which in turn enhance the risk of cardiovascular events. Notably, anti-hypertensive treatment may prevent or regress the changes of arterial wall structures. Lercanidipine is a third-generation CCB with peculiar pharmaceutical properties. Enalapril is an effective drug acting on the renin–angiotensin–aldosterone axis. This commentary discusses the vascular effects of the lercanidipine/enalapril combination, and comments on their potential clinical relevance.