Follicular fluid total antioxidant capacity levels in PCOS. (3rd July 2016)

• Record Type: Journal Article
• Authors: Yilmaz, Nafiye; Inal, Hasan Ali; Gorkem, Umit; Sargin Oruc, Ayla; Yilmaz, Saynur; Turkkani, Ayten
• Is Part Of: Journal of obstetrics and gynaecology. Volume 36:Number 5(2016)
• Page Start: 654
• Page End: 657
• Publication Date: 2016-07-03
• Subjects: Total antioxidant capacity -- follicular fluid -- polycystic ovary syndrome (PCOS) -- assisted reproductive technology (ART) outcomes; Obstetrics -- Periodicals; Gynecology -- Periodicals; 618.05
• DOI: 10.3109/01443615.2016.1148683
• Languages: English
• ISSNs: 0144-3615

Abstract

Abstract : In this study, our aim was to assess total antioxidant capacity (TAC) levels in follicular fluid (FF) and their relationship to clinical pregnancy rates in PCOS patients undergoing assisted reproduction (ART). Twenty-two women with polycystic ovary syndrome (PCOS) (Group 1) and 41 women without PCOS (Group 2) were included in this study. Clinical and laboratory parameters and FF TAC levels were investigated. No statistically significant differences were found between the groups with regard to age and baseline parameters. Although we could not demonstrate a significant difference in FF TAC levels between the two groups ( p =0.469), there was a significant positive correlation between FF TAC and clinical pregnancy rates, BMI, and the duration of infertility for the entire group ( r =0.254, p =0.048; r =0.312, p =0.013; r =0.259, p =0.040; respectively). Owing to the correlation between FF TAC and the clinical pregnancy rates, further studies evaluating the impact of FF TAC levels on ART outcomes in patients with PCOS and other etiologies of infertility are needed.