Peptide retention time prediction. Issue 5 (22nd January 2016)

• Record Type: Journal Article
• Authors: Moruz, Luminita; Käll, Lukas
• Other Names: Valkenborg Dirk guestEditor.
• Is Part Of: Mass spectrometry reviews. Volume 36:Issue 5(2017:Sep./Oct.)
• Page Start: 615
• Page End: 623
• Publication Date: 2016-01-22
• Subjects: bioinformatics -- chromatography -- regression analysis -- mass spectrometry -- peptides; Mass spectrometry -- Periodicals; 543
• DOI: 10.1002/mas.21488
• Languages: English
• ISSNs: 0277-7037

Abstract

Abstract : Most methods for interpreting data from shotgun proteomics experiments are to large degree dependent on being able to predict properties of peptide‐ions. Often such predicted properties are limited to molecular mass and fragment spectra, but here we put focus on a perhaps underutilized property, a peptide's chromatographic retention time. We review a couple of different principles of retention time prediction, and their applications within computational proteomics. © 2016 Wiley Periodicals, Inc. Mass Spec Rev 36:615–623, 2017