Incidental Metastatic Melanoma Identified on 68Ga–Prostate-Specific Membrane Antigen PET/CT for Metastatic Prostate Cancer. (July 2018)

• Record Type: Journal Article
• Authors: Snow, Hayden A.; Hofman, Michael S.; Mitchell, Catherine A.; Gyorki, David E.; Smith, Myles J.F.
• Is Part Of: Clinical nuclear medicine. Volume 43:Number 7(2018)
• Publication Date: 2018-07
• Subjects: Ga PET/CT -- melanoma -- prostate cancer imaging; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000002111
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 78-year-old man with a history of surgically treated prostate cancer and melanoma underwent 68 Ga-prostate-specific membrane antigen (PSMA) PET/CT for biochemical recurrence of his prostate cancer. This revealed locoregionally recurrent prostate cancer and a separate PSMA-avid nodule in his left arm. Subsequent 18 F-FDG PET/CT and excision confirmed this to be an in-transit melanoma metastasis. Prostate-specific membrane antigen PET/CT has become a widely used and valuable tool in the assessment of prostate cancer, particularly biochemically recurrent. Uptake of PSMA has been described in a multitude of different benign and malignant conditions, but it has only rarely been documented in melanoma.