Exercise Training Improves Ventilatory Efficiency in Patients With a Small Abdominal Aortic Aneurysm: A RANDOMIZED CONTROLLED STUDY. Issue 4 (July 2018)

• Record Type: Journal Article
• Authors: Lima, Ricardo M.; Vainshelboim, Baruch; Ganatra, Rucha; Dalman, Ronald; Chan, Khin; Myers, Jonathan
• Is Part Of: Journal of cardiopulmonary rehabilitation and prevention. Volume 38:Issue 4(2018)
• Publication Date: 2018-07
• Subjects: abdominal aortic aneurysm -- cardiorespiratory fitness -- exercise training -- oxygen uptake efficiency slope -- ventilatory efficiency; Cardiopulmonary system -- Diseases -- Patients -- Rehabilitation -- Periodicals; Cardiopulmonary system -- Diseases -- Prevention -- Periodicals; 616.103
• DOI: 10.1097/HCR.0000000000000270
• Languages: English
• ISSNs: 1932-7501

Abstract

Abstract : Purpose: To investigate the effects of exercise training on ventilatory efficiency and physiological responses to submaximal exercise in subjects with small abdominal aortic aneurysm (AAA). Methods: Sixty-five male patients (72.3 ± 7.0 years) were randomized to exercise training (n = 33) or usual care group (n = 32). Exercise subjects participated in a training groups for 3 mo. Cardiopulmonary exercise testing was performed before and after the study period and peak O2, the ventilatory threshold (VT), the oxygen uptake efficiency slope (OUES), and the E2 / CO2 slope were identified. Baseline work rates at VT were matched to examine cardiopulmonary responses after training. Results: Significant interactions indicating improvements before and after training in the exercise group were noted for time ( P < .01), O2 ( P < .01), and work rate ( P < .01) at the VT. At peak effort, significant interactions were noted for time ( P < .01) and work rate ( P < .01), while borderline significance was noted for absolute ( P = .07) and relative ( P = .04) O2 . Significant interactions were observed for the OUES both when using all exercise data ( P = .04) and when calculated up to the VT ( P < .01). For the E2 / CO2 slope, significance was noted only when calculated up to the VT ( P = .04). After training, heart rate, E, O2 and respiratory exchange ratio were significantly attenuated for the same baseline work rate only in the exercise group (all P < .01). Conclusions: Exercise training improves ventilatory efficiency in patients with small AAA. In addition, patients who exercised exhibited less demanding cardiorespiratory responses to submaximal effort. Abstract : We investigated the effects of exercise training on ventilatory efficiency in subjects with small abdominal aortic aneurysm (AAA). Training improved ventilatory efficiency and attenuated cardiorespiratory demand to a matched submaximal work rate. These results suggest a salutary role of exercise therapy in patients awaiting AAA repair.