Arylative Intramolecular Allylation of Ketones with 1, 3‐Enynes Enabled by Catalytic Alkenyl‐to‐Allyl 1, 4‐Rhodium(I) Migration. (19th May 2017)
- Record Type:
- Journal Article
- Title:
- Arylative Intramolecular Allylation of Ketones with 1, 3‐Enynes Enabled by Catalytic Alkenyl‐to‐Allyl 1, 4‐Rhodium(I) Migration. (19th May 2017)
- Main Title:
- Arylative Intramolecular Allylation of Ketones with 1, 3‐Enynes Enabled by Catalytic Alkenyl‐to‐Allyl 1, 4‐Rhodium(I) Migration
- Authors:
- Partridge, Benjamin M.
Callingham, Michael
Lewis, William
Lam, Hon Wai - Abstract:
- Abstract: Alkenyl‐to‐allyl 1, 4‐rhodium(I) migration enables the generation of nucleophilic allylrhodium(I) species by remote C−H activation. This new mode of reactivity was employed in the diastereoselective reaction of arylboron reagents with substrates containing a 1, 3‐enyne tethered to a ketone, to give products containing three contiguous stereocenters. The products can be obtained in high enantioselectivities using a chiral sulfur‐alkene ligand.
- Is Part Of:
- Angewandte Chemie. Volume 129:Number 25(2017)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 129:Number 25(2017)
- Issue Display:
- Volume 129, Issue 25 (2017)
- Year:
- 2017
- Volume:
- 129
- Issue:
- 25
- Issue Sort Value:
- 2017-0129-0025-0000
- Page Start:
- 7333
- Page End:
- 7338
- Publication Date:
- 2017-05-19
- Subjects:
- Allylverbindungen -- Cyclisierungen -- Isomerisierungen -- Reaktionsmechanismen -- Rhodium
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201703155 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 10509.xml