Intermolecular Interactions between Eosin Y and Caffeine Using 1H-NMR Spectroscopy. (10th November 2013)

• Record Type: Journal Article
• Authors: Okuom, Macduff O.; Wilson, Mark V.; Jackson, Abby; Holmes, Andrea E.
• Other Names: Takegami Shigehiko Academic Editor.
• Is Part Of: International journal of spectroscopy. Volume 2013(2013)
• Publication Date: 2013-11-10
• Subjects: Spectrum analysis -- Periodicals; Spectrum Analysis; Spectrum analysis; Periodicals; Periodicals; 543.5
• DOI: 10.1155/2013/245376
• Languages: English
• ISSNs: 1687-9449

Abstract

Abstract : DETECHIP has been used in testing analytes including caffeine, cocaine, and tetrahydrocannabinol (THC) from marijuana, as well as date rape and club drugs such as flunitrazepam, gamma-hydroxybutyric acid (GHB), and methamphetamine. This study investigates the intermolecular interaction between DETECHIP sensor eosin Y (DC1) and the analyte (caffeine) that is responsible for the fluorescence and color changes observed in the actual array. Using 1 H-NMR, 1 H-COSY, and 1 H-DOSY NMR methods, a proton exchange from C-8 of caffeine to eosin Y is proposed.