A highly efficient protocol for the synthesis of new 3-(α-aroylamido)-4hydroxycoumarin derivatives using SnCl2–SiO2 nanoparticles under solventfree conditions. (1st June 2017)

• Record Type: Journal Article
• Authors: Arfavi-Safari, Mona; Anaraki-Ardakani, Hossein; Badri, Rashid; Tahanpesar, Elham
• Is Part Of: Journal of chemical research. Volume 41:Number 6(2017)
• Page Start: 321
• Page End: 324
• Publication Date: 2017-06-01
• Subjects: Chemistry -- Research -- Periodicals; Chemistry -- Periodicals; 540.5
• DOI: 10.3184/174751917X14944355549131
• Languages: English
• ISSNs: 1747-5198

Abstract

An efficient and simple protocol for the synthesis of the title compounds is described via a one-pot, three-component reaction of 4-hydroxycoumarin, aryl glyoxals and amides, using SnCl2–SiO2 nanoparticles as a heterogeneous catalyst under solvent-free conditions. The advantages of this synthesis include excellent yields, mild reaction conditions, atom economy, a reusable catalyst and no need for chromatographic separations.