A facile and diastereoselective access to functionalised benzopyrano[3, 4-a] quinolizines via a pyridine-based three-component reaction. (1st December 2017) - Esmaeili, Abbas Ali
The reaction of 2-oxo-2H-chromene-3-carbonitriles with dialkyl acetylenedicarboxylates and pyridines results in a three-component condensation reaction in which the 2-oxo-2H-chromene-3-carbonitrile group acts as a dipolarophile to produce benzopyrano[3, 4-a] quinolizines under mild conditions in good yield.