1H MR Spectroscopy in Gliomatosis: Is there a Sensitivity Issue?. (11th September 2011)

• Record Type: Journal Article
• Authors: Szewczyk-Bieda, M.; Kanodia, A. K.; Main, G.; Eljamel, M. S.
• Other Names: Fujioka M. Academic Editor.
• Is Part Of: Case reports in radiology. Volume 2011(2011)
• Publication Date: 2011-09-11
• Subjects: Radiology -- Periodicals; Radiology -- Case studies -- Periodicals; Medical radiology -- Periodicals; Radiology; Radiology; Medical radiology; Periodicals; Electronic journals; Case studies; Periodicals; 616.0757
• DOI: 10.1155/2011/371073
• Languages: English
• ISSNs: 2090-6862

Abstract

Abstract : Objective . 1 H MR spectroscopy (MRS) is widely performed for assessment of brain tumours and is considered a highly sensitive technique capable of differentiating benign from malignant conditions and tumour grading. Method . We present a case of a 69 year old woman who was suspected to have gliomatosis on MRI. Results . MRS performed using single voxel and chemical shift/multivoxel techniques was within normal limits. A repeat scan 6 months later showed progressive disease, and biopsy was performed that proved the diagnosis of glioblastoma. Conclusion . Normal MRS in a patient with suspicion of gliomatosis on MRI should not reassure clinicians into assuming a benign aetiology or a good prognosis in short term.