Collagenous Colitis Associated with Protein Losing Enteropathy in a Toddler. (20th August 2014)

• Record Type: Journal Article
• Authors: Almadhoun, Osama F.; Katzman, Philip J.; Rossi, Thomas
• Other Names: Sugimura Haruhiko Academic Editor.
• Is Part Of: Case reports in gastrointestinal medicine. Volume 2014(2014)
• Publication Date: 2014-08-20
• Subjects: Gastroenterology -- Case studies -- Periodicals; Digestive organs -- Diseases -- Periodicals; Gastroenterology; Gastrointestinal Diseases; Digestive organs -- Diseases; Gastroenterology; Electronic journals; Periodicals; Case studies; Periodicals; 616.33
• DOI: 10.1155/2014/209624
• Languages: English
• ISSNs: 2090-6528

Abstract

Abstract : Collagenous mucosal inflammatory disease is a rare gastrointestinal disorder that involves the columnar lining of gastric and intestinal mucosa and is characterized by a distinct subepithelial collagen deposition. Recent clinical and pathological evidence have indicated that collagenous mucosal inflammatory disease can be extensive disease that may concomitantly involve several gastrointestinal sites at the same time. This entity, however, occurs infrequently in children. It is even less common to find concomitant depositions of collagen in the mucosa of gastrointestinal sites other than the colon. Only two cases in pediatric literature reported concomitant involvement, one with gastric and colonic involvement and the other one with gastroduodenocolitis. We are reporting a 15-month-old boy who presented with severe diarrhea and diffuse edema secondary to hypoalbuminemia. Further testing documented protein losing enteropathy (PLE) associated with collagenous colitis.