Premature Menarche Associated with Primary Hypothyroidism in a 5.5-Year-Old Girl. (23rd August 2011)

• Record Type: Journal Article
• Authors: Sharma, Dhrubajyoti; Dayal, Devi; Gupta, Anju; Saxena, Akshay
• Other Names: Moriwaki Yuji Academic Editor.; Simsek Suat Academic Editor.
• Is Part Of: Case reports in endocrinology. Volume 2011(2011)
• Publication Date: 2011-08-23
• Subjects: Endocrinology -- Periodicals; Endocrinology -- Case studies -- Periodicals; Endocrine glands -- Diseases -- Periodicals; Endocrinology; Endocrine System Diseases; Endocrine glands -- Diseases; Endocrinology; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.4
• DOI: 10.1155/2011/678305
• Languages: English
• ISSNs: 2090-6501

Abstract

Abstract : Children with hypothyroidism generally have delayed pubertal development. Rare association with precocious puberty may occur especially in long standing untreated patients. The cardinal features of hypothyroidism induced pseudo precocious pubertal development include thelarche, galactorrhea and menarche. Other characteristics features are an absence of sexual hair and retardation of linear growth. Its manifestation as isolated menarche has been rarely reported. Recently, a five and half year old girl presented to us with history of one episode of vaginal bleeding. A pelvic ultrasonogram revealed multiple cysts in both ovaries and subsequent investigations led to a diagnosis of autoimmune hypothyroidism.