Herpetic Anterior Uveitis – Analysis of Presumed and PCR Proven Cases. (17th February 2019)
- Record Type:
- Journal Article
- Title:
- Herpetic Anterior Uveitis – Analysis of Presumed and PCR Proven Cases. (17th February 2019)
- Main Title:
- Herpetic Anterior Uveitis – Analysis of Presumed and PCR Proven Cases
- Authors:
- Neumann, Ron
Barequet, Dana
Rosenblatt, Amir
Amer, Radgonde
Ben-Arie-Weintrob, Yael
Hareuveni-Blum, Tamar
Vishnevskia-Dai, Vicktoria
Raskin, Eyal
Blumenfeld, Oren
Shulman, Shiri
Sanchez, Juan M.
Flores, Victor
Habot-Wilner, Zohar - Abstract:
- ABSTRACT: Purpose : To describe the demographics and clinical characteristics of patients with herpetic anterior uveitis (HAU), and compare characteristics by pathogen, recurrence, and association to iris atrophy. Methods : Multicenter, retrospective study of AU patients diagnosed clinically and by polymerase chain reaction (PCR). Results : The study included 112 eyes in 109 patients: 54 (48.2%) HSV, 34 (30.4%) VZV, 2 (1.8%) CMV, and 22 (19.6%) unspecified diagnosis. HSV eyes, compared to VZV, had a higher recurrence rate, corneal involvement, KPs, iris atrophy, elevated IOP and posterior synechia ( p < 0.05). VZV patients had more frequent immunomodulatory treatments and history of systemic herpetic disease ( p < 0.05). Fifty-nine (52.7%) eyes had recurrent disease. Iris atrophy was associated with a higher prevalence of posterior synechia, dilated distorted pupil, and high IOP ( p < 0.05). Conclusion : Different HAU-causing Herpesviridae produce common clinical findings; therefore, PCR should be used more often to confirm specific diagnosis. Iris atrophy was associated with more severe disease.
- Is Part Of:
- Ocular immunology and inflammation. Volume 27:Number 2(2019)
- Journal:
- Ocular immunology and inflammation
- Issue:
- Volume 27:Number 2(2019)
- Issue Display:
- Volume 27, Issue 2 (2019)
- Year:
- 2019
- Volume:
- 27
- Issue:
- 2
- Issue Sort Value:
- 2019-0027-0002-0000
- Page Start:
- 211
- Page End:
- 218
- Publication Date:
- 2019-02-17
- Subjects:
- Anterior uveitis -- CMV -- cytomegalovirus -- herpes simplex virus -- herpetic anterior uveitis -- HSV -- PCR -- polymerase chain reaction -- varicella zoster virus -- VZV
Eye -- Diseases -- Immunological aspects -- Periodicals
Eye -- Inflammation -- Periodicals
617.7 - Journal URLs:
- http://informahealthcare.com/loi/oii ↗
http://informahealthcare.com ↗
http://www.tandf.co.uk/journals/titles/09273948.asp ↗ - DOI:
- 10.1080/09273948.2018.1483521 ↗
- Languages:
- English
- ISSNs:
- 0927-3948
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 6235.154200
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 10458.xml