Accuracy of pelvic MRI in measuring tumor height in rectal cancer patients with or without preoperative chemoradiotherapy. Issue 3 (March 2019)

• Record Type: Journal Article
• Authors: Chung, Eric; Kang, Dongwon; Lee, Hye Sun; Cho, Eun-Suk; Kim, Joo Hee; Park, Eun Jung; Baik, Seung Hyuk; Lee, Kang Young; Kang, Jeonghyun
• Is Part Of: European journal of surgical oncology. Volume 45:Issue 3(2019)
• Page Start: 324
• Page End: 330
• Publication Date: 2019-03
• Subjects: Rectal cancer -- Tumor height -- MRI -- Rigid sigmoidoscopy -- Preoperative chemoradiotherapy; Oncology -- Periodicals; Cancer -- Surgery -- Periodicals; Medical Oncology -- Periodicals; Neoplasms -- surgery -- Periodicals; Cancer -- Chirurgie -- Périodiques; Cancérologie -- Périodiques; Oncologie; Chirurgie (geneeskunde); Electronic journals; Electronic journals -- Sciences; Electronic journals -- Medicine; Electronic journals; 616.994059005
• DOI: 10.1016/j.ejso.2018.08.029
• Languages: English
• ISSNs: 0748-7983

Abstract

Abstract: Introduction: In measuring tumor height for rectal cancer, rigid sigmoidoscopy (RS) is a standard modality, and the accuracy of magnetic resonance imaging(MRI) in patients with/without preoperative chemoradiotherapy (CRT) has not been fully investigated. The aim of this study was to investigate the accuracy of MRI for measuring tumor height. Materials and methods: Among rectal cancer patients seen between July 2006 and May 2012, the initial group (RS and MRI available at initial diagnosis) and the post-CRT group (RS and MRI available after the completion of preoperative CRT) were selected. Intra-class correlation coefficient (ICC) comparison tests were performed between RS and MRI results for each group. Results: Ninety-nine and 29 patients were allocated into the initial group and the post-CRT group, respectively. The tumor heights measured by RS and MRI demonstrated a positive relationship in the scatter plot (linear regression; R 2 = 0.898; p < 0.001 in the initial group, R 2 = 0.696; p < 0.001 in the post-CRT group). With respect to difference of absolute value (DAV) between RS and MRI, the overall mean and standard deviation of DAV were 10.9 ± 10 mm in the initial group and 8 ± 6 mm in the post-CRT group. ICC comparison analysis revealed that inter-rater agreement of RS and MRI in the initial group was significantly better than that of the post-CRT group [ICC (95% CI) 0.946 (0.919–0.963) vs. 0.823 (0.621–0.917); p = 0.004)]. Conclusions: MRI can be used as a viable option to measure tumor height in rectal cancer even in patients who have undergone preoperative CRT.