Vision-Related Quality of Life Before and After Deep Anterior Lamellar Keratoplasty. Issue 3 (May 2018)

• Record Type: Journal Article
• Authors: Yildiz, Elvin; Toklu, Meltem; Turan Vural, Ece
• Is Part Of: Eye & contact lens. Volume 44:Issue 3(2018:May)
• Publication Date: 2018-05
• Subjects: Deep anterior lamellar keratoplasty -- Vision-related quality of life -- 25-item National Eye Institute Visual Function Questionnaire -- Keratoplasty; Contact lenses -- Periodicals; Intraocular lenses -- Periodicals; Orthokeratology -- Periodicals; Anterior segment (Eye) -- Diseases -- Periodicals; 617.7523
• DOI: 10.1097/ICL.0000000000000359
• Languages: English
• ISSNs: 1542-2321

Abstract

Abstract : Objectives: To determine changes in the vision-related quality of life in patients undergoing deep anterior lamellar keratoplasty (DALK) by using the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25). Methods: Thirty-five patients who were scheduled for DALK between March 1, 2013, and March 1, 2014 were asked to complete the NEI VFQ-25. NEI VFQ-25 was administered again at 6 months and at 1 year postoperatively. Data on patients' age, sex, preoperative diagnosis, preoperative and postoperative best-corrected visual acuity, and postoperative astigmatism were recorded. Results: Successful DALK with the Anwar big bubble technique was achieved in 23 of 35 (65.7%) patients. The indications for surgery were keratoconus in 15 patients (62.2%), stromal corneal dystrophies in 4 (17%), and corneal scar in 4 (17%). The mean preoperative NEI VFQ-25 composite score (55.2±19.7) improved significantly (76.9±11.6) at 6 months after DALK and continued to improve (84.3±6.6) at 1 year postoperatively (Friedman test, P =0.001). All NEI VFQ-25 subscale item scores increased significantly after surgery. The patients' age was significantly correlated with the NEI VFQ-25 subscale score of mental health at 6 month and at 1 year postoperatively ( r =0.92, P =0.008 and r =0.94, P =0.005, respectively). There was a negative relationship between postoperative astigmatism at 1 year and NEI VFQ-25 ocular pain, social functioning, peripheral vision, and mental health subscale scores ( r =−0.76, P =−0.07; r =−0.53, P =0.2; r =−0.53, P =0.27; r =−0.80, P =0.05). Conclusion: Vision-related quality of life improved significantly after DALK and continued to improve after suture removal.