De Novo Tumors of Teratoma: Ganglioneuroma Arising From a Mature Cystic Teratoma of the Ovary. (May 2018)

• Record Type: Journal Article
• Authors: Coy, Shannon; Meserve, Emily; Berkowitz, Ross; Hirsch, Michelle S.
• Is Part Of: International journal of gynecological pathology. Volume 37:Number 3(2018)
• Publication Date: 2018-05
• Subjects: Teratoma -- Ovary -- Dermoid -- Ganglioneuroma -- Neural crest -- Neuroblastic -- Neurofilament protein; Gynecologic pathology -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; 618.10705
• DOI: 10.1097/PGP.0000000000000409
• Languages: English
• ISSNs: 0277-1691

Abstract

Abstract : Mature teratomas are the most common ovarian neoplasms, accounting for 40% to 50% of ovarian tumors, and are histologically defined by the presence of multiple lineages of mature differentiated cells derived from one or more of the 3 embryonic germ layers; ectoderm, mesoderm, and endoderm. Neuroectodermal and neural crest differentiation can be observed in mature teratomas, but it is uncommon to find secondary tumors that arise from the neural crest lineage. Herein we report the uncommon finding of a ganglioneuroma arising in a mature cystic teratoma in a 26-yr-old woman.