Cells at Wrinkled Interfaces: Laser‐Assisted Strain Engineering of Thin Elastomer Films to Form Variable Wavy Substrates for Cell Culture (Small 21/2019). Issue 21 (24th May 2019)

• Record Type: Journal Article
• Authors: Tomba, Caterina; Petithory, Tatiana; Pedron, Riccardo; Airoudj, Aissam; Di Meglio, Ilaria; Roux, Aurélien; Luchnikov, Valeriy
• Is Part Of: Small. Volume 15:Issue 21(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-05-24
• Subjects: cell curvotaxis -- curvature -- dynamic substrates -- laser treatment -- strain engineering; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.201970113
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : In article number1900162, Caterina Tomba, Valeriy Luchnikov, and co‐workers present a versatile approach to produce curved surfaces with dynamic and variable topographic parameters. Mid‐infrared laser exposure allows for surface stiffening of an elastomer that is suitable as wavy substrate to grow cells on smooth and more realistic micro‐environments. The wrinkled geometry is tuned by controlling the shape and stretching rate of the substrate and the irradiation parameters of the laser. This technique is easily accessible for further studies on cell migration and cell fate determination.