Synthesis of Benzimidazoles through Palladium‐Catalyzed Amination of 2‐Iodobenzimines with Diaziridinone. Issue 4 (20th December 2018)

• Record Type: Journal Article
• Authors: Ma, Ding; Ji, Xiaoming; Wu, Zhuo; Cheng, Cang; Zhou, Bo; Zhang, Yanghui
• Is Part Of: Advanced synthesis & catalysis. Volume 361:Issue 4(2019)
• Page Start: 739
• Page End: 746
• Publication Date: 2018-12-20
• Subjects: Palladacycles -- C−H activation -- Amination -- Palladium -- Benzimidazole; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201801367
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: An efficient approach for the synthesis of benzimidazoles has been developed through the Pd‐catalyzed amination of 2‐iodobenzimines with diaziridinone. A wide range of 2‐(hetero)aryl benzimidazloes are synthesized in good to excellent yields. The reactions likely involve C, C ‐palladacycles derived from 2‐iodobenzimines as the key intermediate, and the palladacycles reacted with diaziridinone to form benzimidazoles. Abstract :