The Use of Topical Corticosteroids for Treatment of Dry Eye Syndrome. (17th February 2019)

• Record Type: Journal Article
• Authors: Cutolo, Carlo Alberto; Barabino, Stefano; Bonzano, Chiara; Traverso, Carlo Enrico
• Is Part Of: Ocular immunology and inflammation. Volume 27:Number 2(2019)
• Page Start: 266
• Page End: 275
• Publication Date: 2019-02-17
• Subjects: Chronic inflammation -- corticosteroids -- dry eye -- glucocorticoids -- ocular surface; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2017.1341988
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Dry eye disease (DED) is a multifactorial disease that results in symptoms of discomfort, visual disturbance, and damage to the ocular surface. Because chronic inflammation plays an important role in DED, treatment with topical corticosteroids has been demonstrated to ameliorate the signs and symptoms of the disease. Although these agents have proven short-term efficacy, their long-term use may cause intraocular pressure elevation and cataract progression. A carefully review of the different studies shows that differences between corticosteroids may exist regarding the incidence of side effects and evidence of efficacy in DED patients.