Photocatalytic aerobic α-thiolation/annulation of carbonyls with mercaptobenzimidazoles. Issue 20 (7th May 2019)

• Record Type: Journal Article
• Authors: Ji, Xiaochen; Tan, Muyun; Fu, Mei; Deng, Guo-Jun; Huang, Huawen
• Is Part Of: Organic & biomolecular chemistry. Volume 17:Issue 20(2019)
• Page Start: 4979
• Page End: 4983
• Publication Date: 2019-05-07
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c9ob00625g
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A concise aerobic photocatalysis using a blue LED combined with a Lewis acid has been developed to enable α-thiolation/annulation of carbonyls. Abstract : A concise aerobic photocatalysis using a blue LED combined with a Lewis acid has been developed to enable α-thiolation/annulation of carbonyls. Inexpensive, nontoxic Rose Bengal was demonstrated as the best catalyst. Hence, this transition-metal-free protocol allows mild Csp 3 –S couplings with both ketones and aliphatic aldehydes with a range of compatible useful functionalities.