Base-promoted regiodivergent allylation of N-acylhydrazones with Morita–Baylis–Hillman carbonates by tuning the catalyst. Issue 21 (15th May 2019)

• Record Type: Journal Article
• Authors: Sun, Fang; Yin, Tingrui; Feng, Anni; Hu, Yong; Yu, Chenxia; Li, Tuanjie; Yao, Changsheng
• Is Part Of: Organic & biomolecular chemistry. Volume 17:Issue 21(2019)
• Page Start: 5283
• Page End: 5293
• Publication Date: 2019-05-15
• Subjects: Chemistry, Organic -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1039/c9ob00194h
• Languages: English
• ISSNs: 1477-0520

Abstract

Abstract : A catalyst-controlled regiodivergent allylation reaction of N -acylhydrazones (NAHs) with Morita–Baylis–Hillman (MBH) carbonates has been developed, paving a new avenue for the diversification of NAH. Abstract : A regiodivergent allylation of N -acylhydrazones with Morita–Baylis–Hillman (MBH) carbonates has been developed, providing α- or γ-allylated products in excellent yields by using different catalysts. The nature of the base catalyst plays a pivotal role in controlling the reaction pathway, allowing regiospecific access to diverse allylic substituted target compounds from identical substrates.