Fat Embolism Syndrome in Duchenne Muscular Dystrophy Patients: Early Recognition and Aggressive Therapy. (4th June 2018)

• Record Type: Journal Article
• Authors: Murphy, Lee D.; Yabrodi, Mouhammad; Lutfi, Riad
• Other Names: Lazzeri Chiara Academic Editor.
• Is Part Of: Case reports in critical care. Volume 2018(2018)
• Publication Date: 2018-06-04
• Subjects: Critical care medicine -- Periodicals; Emergency medicine -- Periodicals; Medical emergencies -- Periodicals; 616.02805
• DOI: 10.1155/2018/3686470
• Languages: English
• ISSNs: 2090-6420

Abstract

Abstract : We describe two pediatric patients with Duchenne muscular dystrophy that presented with acute neurologic deterioration and hypoxic respiratory failure requiring mechanical ventilation. These cases fulfill the clinical criteria for Fat Embolism Syndrome. Early recognition and aggressive supportive therapy with mechanical ventilation, right ventricular afterload reduction, and blood transfusion led to survival without any residual effects from the event. Fat Embolism Syndrome needs to be considered early in the course of patients with Duchenne muscular dystrophy who present with respiratory and neurological symptoms.