Coumarins and other components of Daphne oleoides Schreb. subsp. oleoides from Majella National Park. (April 2019)

• Record Type: Journal Article
• Authors: Venditti, Alessandro; Serrilli, Anna Maria; Di Cecco, Mirella; Ciaschetti, Giampiero; Bianco, Armandodoriano
• Is Part Of: Biochemical systematics and ecology. Volume 83(2019)
• Page Start: 39
• Page End: 46
• Publication Date: 2019-04
• Subjects: Daphne oleoides Schreb. subsp. oleoides -- Thymelaeaceae -- Secondary metabolites -- Chemotaxonomy -- Infraspecific chemovariability; Chemotaxonomy -- Periodicals; Biochemical variation -- Periodicals; Ecology -- Periodicals; Biochemistry -- Periodicals; Ecology -- Periodicals; Chimiotaxinomie -- Périodiques; Variation biochimique -- Périodiques; Écologie -- Périodiques; 578.012
• DOI: 10.1016/j.bse.2018.12.013
• Languages: English
• ISSNs: 0305-1978

Abstract

Abstract: The present study reports about the phytochemical analysis of a sample of Daphne oleoides Schreb. subsp. oleoides (family Thymelaeaceae) collected from the Majella National Park. Twenty components, belonging to different classes of natural products, have been identified by means of spectroscopic and spectrometric techniques: [monomeric (4 ), bis- (5, 7 –10, 20 ) and trimeric coumarins (11 ), including aglycones and glycosides, coumarinolignoid (6 ); flavonoids (16 –19 ); glycosidic furolignans (14, 15 ), glucosidic phenylpropanoids (12, 13 ), cyclic tetrapyrrole derivatives (2, 3 ), unsaturated triglyceride (1 )]. Besides the chemosystematic markers of the genus (4 –10, 12, 14 –18, 20 ) several other components were identified for the first time in the species (17, 20 ) and/or in the Daphne genus (1 –3, 13, 19 ). The observed composition was discussed from the chemotaxonomic standpoint and compared with those recognized from a Sardinian accession. It was observed a pronounced difference in the two metabolites patterns, most probably attributable to geographic isolation of the studied populations and, in some extent, also by the different environmental conditions, evidencing a possible tendency of D. oleoides to the infraspecific chemovariability. Considering the wide traditional uses of Daphne spp. in ethnomedicine of several countries, also the pharmacologic potential of the identified secondary metabolites is discussed. Highlights: The first analysis of D. oleoides from the Majella National Park is reported. Twenty phytochemicals were identified. The chemotaxonomy relevance of isolated compounds is discussed. Infraspecific chemovariability, possibly due to the environment, was observed. D. oleoides could be a possible source of bioactive secondary metabolites.