Brugada Syndrome and Pregnancy: Highlights on Antenatal and Prenatal Management. (22nd May 2014)
- Record Type:
- Journal Article
- Title:
- Brugada Syndrome and Pregnancy: Highlights on Antenatal and Prenatal Management. (22nd May 2014)
- Main Title:
- Brugada Syndrome and Pregnancy: Highlights on Antenatal and Prenatal Management
- Authors:
- Giambanco, Laura
Incandela, Domenico
Maiorana, Antonio
Alio, Walter
Alio, Luigi - Other Names:
- Kauffman R. P. Academic Editor.
Porpora M. G. Academic Editor.
Salhan S. Academic Editor. - Abstract:
- Abstract : Introduction . Brugada syndrome is characterized by a disruption of heart's normal rhythm. It is an autosomal dominant disease due to a mutation of SNC5A gene. Its prevalence is low all over the world, but it is a lethal disease. Sudden cardiac death is the result of phenotypic manifestation of Brugada syndrome. Among asymptomatic Brugada patients, arrhythmia could be provoked by physical activity, fever, or pregnancy. About obstetrical management, very few data or reports have been published since this syndrome has been diagnosed in late 1992. Case Presentation . A 20-year-old pregnant woman at 13 weeks of gestation was referred to our department because of her familial history of sudden cardiac deaths. Brothers and sisters of her mother died of Brugada syndrome in childhood or older and live components of this family were carrier of mutation in Brugada gene. The pregnancy was uneventful. The patient gave birth vaginally without any arrhythmia. Strictly cardiological monitoring was performed during labour, delivery, and 12 hours of the postpartum. Conclusion . Even though patient at low risk may never have arrhythmia, some conditions could represent a Brugada trigger. The management could be very easy and uneventful. Otherwise it could be very difficult with need of ECMO or antiarrhythmics drugs or intracardiac device. Obstetrical management of Brugada pregnant women should be very strict and multidisciplinary in cooperation with cardiologist andAbstract : Introduction . Brugada syndrome is characterized by a disruption of heart's normal rhythm. It is an autosomal dominant disease due to a mutation of SNC5A gene. Its prevalence is low all over the world, but it is a lethal disease. Sudden cardiac death is the result of phenotypic manifestation of Brugada syndrome. Among asymptomatic Brugada patients, arrhythmia could be provoked by physical activity, fever, or pregnancy. About obstetrical management, very few data or reports have been published since this syndrome has been diagnosed in late 1992. Case Presentation . A 20-year-old pregnant woman at 13 weeks of gestation was referred to our department because of her familial history of sudden cardiac deaths. Brothers and sisters of her mother died of Brugada syndrome in childhood or older and live components of this family were carrier of mutation in Brugada gene. The pregnancy was uneventful. The patient gave birth vaginally without any arrhythmia. Strictly cardiological monitoring was performed during labour, delivery, and 12 hours of the postpartum. Conclusion . Even though patient at low risk may never have arrhythmia, some conditions could represent a Brugada trigger. The management could be very easy and uneventful. Otherwise it could be very difficult with need of ECMO or antiarrhythmics drugs or intracardiac device. Obstetrical management of Brugada pregnant women should be very strict and multidisciplinary in cooperation with cardiologist and anaesthesiologist and should provide an informed consent to the couple. … (more)
- Is Part Of:
- Case reports in obstetrics and gynecology. Volume 2014(2014)
- Journal:
- Case reports in obstetrics and gynecology
- Issue:
- Volume 2014(2014)
- Issue Display:
- Volume 2014, Issue 2014 (2014)
- Year:
- 2014
- Volume:
- 2014
- Issue:
- 2014
- Issue Sort Value:
- 2014-2014-2014-0000
- Page Start:
- Page End:
- Publication Date:
- 2014-05-22
- Subjects:
- Obstetrics -- Periodicals
Gynecology -- Periodicals
Generative organs, Female -- Diseases -- Periodicals
Obstetrics
Gynecology
Genital Diseases, Female
Generative organs, Female -- Diseases
Gynecology
Obstetrics
Electronic journals
Periodicals
Periodicals
618 - Journal URLs:
- https://www.hindawi.com/journals/criog/ ↗
http://bibpurl.oclc.org/web/49078 ↗
http://www.ncbi.nlm.nih.gov/pmc/journals/1776/ ↗
http://search.ebscohost.com/direct.asp?db=a9h&jid=%22EGTE%22&scope=site ↗ - DOI:
- 10.1155/2014/531648 ↗
- Languages:
- English
- ISSNs:
- 2090-6684
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library HMNTS - ELD Digital store
- Ingest File:
- 10417.xml