Lifespan leisure physical activity profile, brain plasticity and cognitive function in old age. (3rd July 2019)

• Record Type: Journal Article
• Authors: Engeroff, Tobias; Vogt, Lutz; Fleckenstein, Johannes; Füzéki, Eszter; Matura, Silke; Pilatus, Ulrich; Schwarz, Sina; Deichmann, Ralf; Hellweg, Rainer; Pantel, Johannes; Banzer, Winfried
• Is Part Of: Aging & mental health. Volume 23:Number 7(2019)
• Page Start: 811
• Page End: 818
• Publication Date: 2019-07-03
• Subjects: Neuropsychology -- brain metabolism -- brain structure -- neurobiology -- brain derived neurotropic factor -- exercise -- lifelong -- lifetime; Older people -- Mental health -- Periodicals; Geriatric psychiatry -- Periodicals; Older people -- Psychology -- Periodicals; Aging -- Psychological aspects -- Periodicals; Aged -- psychology -- periodicals; Mental Health -- periodicals; Mental Health Services -- periodicals; Aging -- psychology -- periodicals; Aged, 80 and over -- psychology -- periodicals; 618.97689
• DOI: 10.1080/13607863.2017.1421615
• Languages: English
• ISSNs: 1360-7863

Abstract

ABSTRACT: Objectives: Despite the evidence suggesting physical activity (PA) as a major factor for the prevention of age-related cognitive decline, only a few studies have systematically investigated the impact of leisure PA during the lifespan (LLPA). This study investigates the effects of LLPA on cognitive function (CF) and brain plasticity (BP) in old age. Method: Participants' ( n = 50, 72 ± 5 yrs, 27 females) LLPA energy expenditure and volume was assessed via a validated questionnaire investigating five epochs (14–80 yrs). Using current WHO PA recommendations as reference, participants were stratified into energy expenditure and volume groups. CF outcomes were attention, executive functions, working memory and memory. BP was assessed using magnetic resonance spectroscopy (MRSI) and brain derived neurotropic factor (BDNF). Results: Correlation analysis revealed associations of mean LLPA energy expenditure with attention (CF) and N-acetylaspartate to choline ratios (NAA/Cho) (MRSI). ANOVA revealed higher interference control performance (CF) and NAA/Cho in participants complying with current PA recommendations (2-3 h per week) compared to non-compliers. Further CF and BP outcomes including BDNF were not associated with LLPA. Conclusion: Lifelong adherence to minimum recommended PA seems to be associated with markers of cognitive function and neuronal integrity in old age.