Amphiphilic hydrogels for biomedical applications. Issue 18 (18th April 2019)

• Record Type: Journal Article
• Authors: Chang, Heng; Li, Chuanxi; Huang, Renliang; Su, Rongxin; Qi, Wei; He, Zhimin
• Is Part Of: Journal of materials chemistry. Volume 7:Issue 18(2019)
• Page Start: 2899
• Page End: 2910
• Publication Date: 2019-04-18
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c9tb00073a
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : We highlight the recent advances in the fabrication and biomedical application of amphiphilic hydrogels. Abstract : Polymeric biomaterials, especially biodegradable polymers, have been extensively applied in biomedical applications. Amphiphilic hydrogels containing both hydrophilic and hydrophobic units represent one major class of polymeric biomaterials. Here, we review the fabrication and properties of hydrogels derived from different amphiphiles, as well as their biomedical applications. Amphiphilic peptides have become increasingly attractive in the development of self-assembling hydrogels because of their biological origin. Numerous polysaccharides have also been made amphiphilic as hydrogels, for their good biocompatibility and plentiful functional groups to facilitate chemical modification. Amphiphilic hydrogels have been widely used for drug delivery, tissue engineering, antibacterial activity, and other biomedical applications due to their advantages such as biocompatibility, nontoxicity, controlled biodegradability, and responsiveness to environmental stimuli.