Are young women ready for BRCA testing? Comparing attitudes and comprehension of two age groups of healthy Italian women. Issue 6 (June 2019)

• Record Type: Journal Article
• Authors: Gavaruzzi, Teresa; Tasso, Alessandra; Franiuk, Marzena; Varesco, Liliana; Lotto, Lorella
• Is Part Of: Patient education and counseling. Volume 102:Issue 6(2019)
• Page Start: 1210
• Page End: 1216
• Publication Date: 2019-06
• Subjects: BRCA mutation -- Breast and ovarian cancer -- Oncology -- Preventive genetic testing -- Young women; Patient education -- Periodicals; Health counseling -- Periodicals; Health education -- Periodicals; Counseling -- Periodicals; Patient Education -- Periodicals; Éducation des patients -- Périodiques; Counseling -- Périodiques; Éducation sanitaire -- Périodiques; 615.5071
• DOI: 10.1016/j.pec.2019.01.022
• Languages: English
• ISSNs: 0738-3991

Abstract

Highlights: Young healthy women showed positive attitudes towards genetic BRCA testing. Young healthy women had a lower comprehension of BRCA information than adult healthy women. Young women had a lower comprehension of the consequences of testing. Young women incorrectly identified the risk figures of breast and ovarian cancer. Young women showed more frequent errors when answering open-ended questions. Abstract: Background: Mutations in the BRCA 1/2 genes increase the risk of developing breast and/or ovarian cancer compared with the general population. However, the risk is lowat age 30, and for women younger than 25, no preventive or screening options are available. Scientists wonder whether genetic predictive BRCA testing is appropriate at a very young age. Furthermore, although young women have positive attitudes toward testing, their understanding of genetic information seems scarce. Objective: To assess how young (18–24) versus adult (30–45) women at general population- level risk understand information about BRCA testing. Methods: 302 women read an informative pamphlet and answered an ad-hoc questionnaire assessing usefulness of the information for decision making, intention to undergo predictive testing, and comprehension (perceived, general, and risk comprehension; open-ended questions). Results: Younger women had a lower comprehension of important BRCA information; it was more difficult for young women to identify the risk figures of cancer, and they showed errors when answering open-ended questions. Limitations: Results are limited bythe study's hypothetical nature. Conclusions: Young women seem to have particular difficulty understanding BRCA information. Practice implications: Counsellors should be aware of the difficulties young women have in understanding information about BRCA predictive testing.