Anticancer Activities of Tumor-killing Nanorobots. Issue 6 (June 2019)

• Record Type: Journal Article
• Authors: Li, Suping; Jiang, Qiao; Ding, Baoquan; Nie, Guangjun
• Is Part Of: Trends in biotechnology. Volume 37:Issue 6(2019)
• Page Start: 573
• Page End: 577
• Publication Date: 2019-06
• Subjects: thrombin -- DNA nanorobot -- active tumor targeting -- vascular infarction; Biotechnology -- Periodicals; Biochemical engineering -- Periodicals; Genetic engineering -- Periodicals; Industrial microbiology -- Periodicals; 660.605
• DOI: 10.1016/j.tibtech.2019.01.010
• Languages: English
• ISSNs: 0167-7799

Abstract

Abstract : Pharmaceutical uses of cancer therapeutics, such as intravenous thrombin to elicit blood coagulation, have been hampered by lack of tumor specificity. Based on rapid progress in DNA origami-based machines capable of transporting molecular payloads, DNA nanorobots have been constructed to specifically deliver therapeutic agents into tumor vessels.