Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature. (7th May 2015)

• Record Type: Journal Article
• Authors: Granata, Guido; Didona, Dario; Stifano, Giuseppina; Feola, Aldo; Granata, Massimo
• Other Names: Kalunian Kenneth C. Academic Editor.
• Is Part Of: Case reports in medicine. Volume 2015(2015)
• Publication Date: 2015-05-07
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Case Reports; Periodicals; 610
• DOI: 10.1155/2015/294041
• Languages: English
• ISSNs: 1687-9627

Abstract

Abstract : Macrophage activation syndrome (MAS) is a potentially fatal condition. It belongs to the hemophagocytic lymphohistiocytosis group of diseases. In adults, MAS is rarely associated with systemic lupus erythematosus, but it also arises as complication of several systemic autoimmune disorders, like ankylosing spondylitis, rheumatoid arthritis, and adult-onset Still's disease. Several treatment options for MAS have been reported in the literature, including a therapeutic regimen of etoposide, dexamethasone, and cyclosporine. Here we report a case of 42-year-old woman in whom MAS occurred as onset of systemic lupus erythematosus.