Gastric tumours. (May 2019)

• Record Type: Journal Article
• Authors: Knight, William R.; Allum, William H.
• Is Part Of: Medicine. Volume 47:Number 5(2019)
• Page Start: 309
• Page End: 313
• Publication Date: 2019-05
• Subjects: Gastric adenocarcinoma -- gastric lymphoma -- gastrointestinal stromal tumour -- MRCP; Medicine -- Periodicals; Medicine -- Periodicals; Médecine -- Périodiques; Médecine factuelle -- Périodiques; Medicine; Periodicals; Electronic journals; Electronic journals; 610
• DOI: 10.1016/j.mpmed.2019.02.002
• Languages: English
• ISSNs: 1357-3039

Abstract

Abstract: Gastric tumours are subdivided into those of epithelial and stromal origin. Malignant tumours are more common than benign, with adenocarcinomas being the most common type of malignancy. Rarer gastric malignancies include gastrointestinal stromal tumours (GISTs), lymphomas and neuro-endocrine tumours. Gastric cancer is the sixth most common cancer in Europe and the fourth most common cause of cancer death. Multidisciplinary treatment planning is an essential part of management of these cancers. The only curative treatment option is surgical resection, although this is usually accompanied by perioperative chemotherapy or adjuvant chemoradiotherapy. GISTs are most commonly caused by a mutation in the KIT gene. They are the most common mesenchymal malignancies of the gastrointestinal tract and are usually found in the stomach. Intestinal lymphomas are also most commonly found in the stomach, and most arise from the mucosa-associated lymphoid tissue.