Discrepancies between Antimullerian Hormone and Follicle Stimulating Hormone in Assisted Reproduction. (18th December 2013)

• Record Type: Journal Article
• Authors: Hussain, Munawar; Cahill, David; Akande, Valentine; Gordon, Uma
• Other Names: Hernandez Enrique Academic Editor.
• Is Part Of: Obstetrics and gynecology international. Volume 2013(2013)
• Publication Date: 2013-12-18
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; 618.1005
• DOI: 10.1155/2013/383278
• Languages: English
• ISSNs: 1687-9589

Abstract

Abstract : Data from 107 women undergoing their first IVF/ICSI were analyzed. Relationships between antimullerian hormone (AMH) and follicle stimulating hormone (FSH) were analyzed after dividing patients into four groups according to AMH/FSH levels. Concordance was noted in 57% of women (both AMH/FSH either normal or abnormal) while 43%of women had discordant values (AMH/FSH one hormone normal and the other abnormal). Group 1 (AMH and FSH in normal range) and group 2 (normal AMH and high FSH) were younger compared to group 3 (low AMH and normal FSH) and group 4 (both AMH/FSH abnormal). Group 1 showing the best oocyte yield was compared to the remaining three groups. Groups 3 and 4 required higher dose of gonadotrophins for controlled ovarian hyperstimulation showing their low ovarian reserve. There was no difference in cycle cancellation, clinical pregnancy, and live birth/ongoing pregnancy rate in all groups. These tests are useful to predict ovarian response but whether AMH is a substantially better predictor is not yet established.