Do Neural Cells Communicate with Endothelial Cells via Secretory Exosomes and Microvesicles?. (21st July 2009)

• Record Type: Journal Article
• Authors: Smalheiser, Neil R.
• Other Names: Manev Hari Academic Editor.
• Is Part Of: Cardiovascular psychiatry and neurology. Volume 2009(2009)
• Publication Date: 2009-07-21
• Subjects: Cardiovascular system -- Diseases -- Periodicals; Cardiovascular system -- Diseases -- Psychological aspects -- Periodicals; Psychiatry -- Periodicals; Cardiology -- Periodicals; Neurology -- Periodicals; Nervous system -- Diseases -- Periodicals; Cardiology; Cardiovascular system -- Diseases; Cardiovascular system -- Diseases -- Psychological aspects; Nervous system -- Diseases; Neurology; Psychiatry; Cardiovascular Diseases -- complications; Nervous System Diseases -- complications; Mental Disorders -- complications; Cardiology; Neurology; Psychiatry; Cardiovascular Diseases -- complications -- Periodicals; Nervous System Diseases -- complications -- Periodicals; Mental Disorders -- complications -- Periodicals; Cardiology -- Periodicals; Neurology -- Periodicals; Psychiatry -- Periodicals; Periodicals; Electronic journals; 616.81
• DOI: 10.1155/2009/383086
• Languages: English
• ISSNs: 2090-0163

Abstract

Abstract : Neurons, glial, cells, and brain tumor cells tissues release small vesicles (secretory exosomes and microvesicles), which may represent a novel mechanism by which neuronal activity could influence angiogenesis within the embryonic and mature brain. If CNS-derived vesicles can enter the bloodstream as well, they may communicate with endothelial cells in the peripheral circulation and with cells concerned with immune surveillance.