A Case of Levamisole-Induced Agranulocytosis. (11th February 2018)

• Record Type: Journal Article
• Authors: Kassim, Thamer; Chintalacheruvu, Lakshmi; Bhatty, Osman; Selim, Mohammad; Diab, Osama; Nayfeh, Ali; Manikkam Umakanthan, Jayadev; Gbadamosi-Akindele, Maryam
• Other Names: Murdaca Giuseppe Academic Editor.
• Is Part Of: Case reports in hematology. Volume 2018(2018)
• Publication Date: 2018-02-11
• Subjects: Hematology -- Periodicals; Hematology -- Case studies -- Periodicals; Blood -- Diseases -- Periodicals; Hematology; Hematologic Diseases; Blood -- Diseases; Hematology; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.15
• DOI: 10.1155/2018/7341835
• Languages: English
• ISSNs: 2090-6560

Abstract

Abstract : A sixty-eight-year-old male with a past medical history of recurrent cocaine use presented to the emergency department with recurrent diarrhea and was found to have a white blood cell (WBC) count of 1.9 × 10 9 /L with agranulocytosis (absolute neutrophil count (ANC) of 95 cell/mm 3 ). At admission, the patient disclosed that he used cocaine earlier during the day, and a urine drug screen tested positive for this. On hospital day one, the patient was found to have a fever with a maximum temperature of 313.6 K. After ruling out other causes and noting the quick turnaround of his neutropenia after four days of cocaine abstinence, the patient's neutropenia was attributed to levamisole-adulterated cocaine.