Lenalidomide-Associated ITP. (17th July 2011)

• Record Type: Journal Article
• Authors: Herold, Christina I.; Gasparetto, Cristina; Arepally, Gowthami M.
• Other Names: Kyrtsonis M.-C. Academic Editor.; Sonoki T. Academic Editor.; Storti S. Academic Editor.; Várkonyi J. Academic Editor.; Wagner S. D. Academic Editor.
• Is Part Of: Case reports in hematology. Volume 2011(2011)
• Publication Date: 2011-07-17
• Subjects: Hematology -- Periodicals; Hematology -- Case studies -- Periodicals; Blood -- Diseases -- Periodicals; Hematology; Hematologic Diseases; Blood -- Diseases; Hematology; Electronic journals; Periodicals; Case studies; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.15
• DOI: 10.1155/2011/638020
• Languages: English
• ISSNs: 2090-6560

Abstract

Abstract : Lenalidomide is a potent immunomodulatory agent being used increasingly for treatment of hematologic malignancies including multiple myeloma and myelodysplasia. The common toxicities of lenalidomide, including dose-limiting myelosuppression, are well described. However, the immunomodulatory properties of lenalidomide may give rise to unexpected autoimmune complications. Herein, we describe a case of immune thrombocytopenic purpura (ITP) associated with use of lenalidomide.