Reliable Prediction of Insulin Resistance by a School-Based Fitness Test in Middle-School Children. (17th September 2009)

• Record Type: Journal Article
• Authors: Varness, Todd; Carrel, Aaron L.; Eickhoff, Jens C.; Allen, David B.
• Other Names: Genel Myron Academic Editor.
• Is Part Of: International journal of pediatric endocrinology. Volume 2009(2009)
• Publication Date: 2009-09-17
• Subjects: Pediatric endocrinology -- Periodicals; Endocrine glands -- Diseases -- Periodicals; 618.924
• DOI: 10.1155/2009/487804
• Languages: English
• ISSNs: 1687-9856

Abstract

Abstract : Objectives . (1) Determine the predictive value of a school-based test of cardiovascular fitness (CVF) for insulin resistance (IR); (2) compare a "school-based" prediction of IR to a "laboratory-based" prediction, using various measures of fitness and body composition. Methods . Middle school children (n = 82 ) performed the Progressive Aerobic Cardiovascular Endurance Run (PACER), a school-based CVF test, and underwent evaluation of maximal oxygen consumption treadmill testing (VO 2 max), body composition (percent body fat and BMI z score), and IR (derived homeostasis model assessment index [HOMA IR ]). Results . PACER showed a strong correlation withVO 2 max/kg (r s = 0.83, P < .001 ) and withHOMA IR (r s =− 0.60, P < .001 ). Multivariate regression analysis revealed that a school-based model (using PACER and BMI z score) predicted IR similar to a laboratory-based model (usingVO 2 max/kg of lean body mass and percent body fat). Conclusions . The PACER is a valid school-based test of CVF, is predictive of IR, and has a similar relationship to IR when compared to complex laboratory-based testing. Simple school-based measures of childhood fitness (PACER) and fatness (BMI z score) could be used to identify childhood risk for IR and evaluate interventions.