Determination of Sinomenine in Cubosome Nanoparticles by HPLC Technique. (5th February 2015)

• Record Type: Journal Article
• Authors: Zhou, Yanfang; Guo, Chunlian; Chen, Hongying; Zhang, Yudai; Peng, Xinsheng; Zhu, Ping
• Other Names: Simal-Gandara Jesus Academic Editor.
• Is Part Of: Journal of analytical methods in chemistry. Volume 2015(2015)
• Publication Date: 2015-02-05
• Subjects: Chemistry, Analytic -- Periodicals; Chemistry, Analytic -- Technique -- Periodicals; 543.05
• DOI: 10.1155/2015/931687
• Languages: English
• ISSNs: 2090-8865

Abstract

Abstract : We applied HPLC technique to quantitatively analyze sinomenine in cubosome nanoparticles. The chromatographic method was performed by using an isocratic system. The mobile phase was composed of methanol-PBS(pH6.8)-triethylamine (50 : 50 : 0.1%) with a flow rate of 1 mL/min; the detection wavelength was at 265 nm. Sinomenine can be successfully separated with good linearity (the regression equation isA = 10 835 C + 1058 ;R 2 = 1.0 ) and perfect recovery (102.2%). The chromatograph technique was proper for quality control of sinomenine in cubosome nanoparticles.