Mesenchymal Stem Cell Conditioned Media Ameliorate Psoriasis Vulgaris: A Case Study. (2nd May 2019)

• Record Type: Journal Article
• Authors: Seetharaman, Rajasekar; Mahmood, Anjum; Kshatriya, Prashant; Patel, Divyang; Srivastava, Anand
• Other Names: Szepietowski Jacek Cezary Academic Editor.
• Is Part Of: Case reports in dermatological medicine. Volume 2019(2019)
• Publication Date: 2019-05-02
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; 616.5005
• DOI: 10.1155/2019/8309103
• Languages: English
• ISSNs: 2090-6463

Abstract

Abstract : Psoriasis, an autoimmune disease, affects a vast number of peoples around the world. In this report, we discuss our findings about a scalp psoriasis suffering patient with a Psoriasis Scalp Severity Index (PSSI) score of 28, who was treated with Mesenchymal stem cell conditioned media (MSC-CM). Remarkably, complete regression was recorded within a treatment period of one month only (PSSI score of 0). A number of bioactive factors like cytokines and growth factors secreted by MSCs in the conditioned medium are very likely to be the principle molecules which play a vital role in skin regeneration. Treatment using MSC-CM appears to be an effective tool for tackling the psoriatic problem and, thus, may offer a new avenue of therapy which could be considered as an alternative approach to overcome the limitations of the cell-based therapy.