Flow rate estimation of a centrifugal blood pump using the passively stabilized eccentric position of a magnetically levitated impeller. Issue 6 (June 2019)

• Record Type: Journal Article
• Authors: Shida, Shuya; Masuzawa, Toru; Osa, Masahiro
• Is Part Of: International journal of artificial organs. Volume 42:Issue 6(2019)
• Page Start: 291
• Page End: 298
• Publication Date: 2019-06
• Subjects: Flow rate estimation -- magnetically levitated impeller -- centrifugal blood pump -- passive stabilization -- eccentric impeller position; Artificial organs -- Periodicals; 617.956
• DOI: 10.1177/0391398819833372
• Languages: English
• ISSNs: 0391-3988

Abstract

Flow rate estimation for ventricular assist devices without additional flow sensors can improve the quality of life of patients. In this article, a novel flow estimation method using the passively stabilized displacement of a magnetically levitated impeller is developed to achieve sufficient accuracy and precision of flow estimation for ventricular assist devices in a simple manner. The magnetically levitated impeller used is axially suspended by a magnetic bearing in a centrifugal blood pump that has been developed by our group. The radial displacement of the impeller, which is restricted by passive stability, can be correlated with the flow rate because the radial hydraulic force on the impeller varies according to the flow rate. To obtain the correlation with various blood viscosities, the relationships between the radial displacements of the magnetically levitated impeller and the pressure head-flow rate characteristics of the pump were determined simultaneously using aqueous solutions of glycerol with a potential blood viscosity range. The measurement results showed that accurate steady flow rates could be estimated with a coefficient of determination of approximately 0.97 and mean absolute error of approximately 0.22 L/min without fluid viscosity measurements by using the relationships between the impeller displacement and the flow rate. Moreover, a precision of approximately 0.01 (L/min)/µm was obtained owing to a strong estimation indicator signal provided by the large displacement of the passively stabilized impeller; thus, the proposed estimation method can help ensure sufficient accuracy and precision for ventricular assist devices in a simple manner, even if the blood viscosity is unknown.