Cationic Porphyrin Induced a Telomeric DNA to G-Quadruplex Form in Water. (21st January 2008)

• Record Type: Journal Article
• Authors: Murashima, Takashi; Sakiyama, Daichi; Miyoshi, Daisuke; Kuriyama, Masanori; Yamada, Takashi; Miyazawa, Toshifumi; Sugimoto, Naoki
• Other Names: Brabec Viktor Academic Editor.
• Is Part Of: Bioinorganic chemistry and applications. Volume 2008(2008)
• Publication Date: 2008-01-21
• Subjects: Bioinorganic chemistry -- Periodicals; Bioinorganic chemistry; Biochemistry; Inorganic Chemistry; Chemistry, Bioinorganic; Periodicals; 572.51
• DOI: 10.1155/2008/294756
• Languages: English
• ISSNs: 1565-3633

Abstract

Abstract : The formation of the DNA G-quadruplex is induced by the addition of a novel porphyrin carrying four cationic tethers. Circular dichroism spectroscopy reveals that the porphyrin binds to Tetrahymena telomeric repeat to form G-quadruplex under stabilizing-cation-deficient and no buffer conditions.