Villous Adenoma Arising in the Native Bladder Mucosa and the Upper Urinary Tract With Coexisting Neuroendocrine Carcinoma Following Augmentation Cystoplasty. (June 2019)

• Record Type: Journal Article
• Authors: Nayak, Anupma; Depasquale, Brittany; Vergara, Norge; Guzzo, Thomas A.; Lal, Priti
• Is Part Of: International journal of surgical pathology. Volume 27:Number 4(2019)
• Page Start: 450
• Page End: 456
• Publication Date: 2019-06
• Subjects: villous adenoma -- augmentation cystoplasty -- native bladder mucosa -- neuroendocrine carcinoma -- renal pelvis -- ureters; Pathology, Surgical -- Periodicals; 617.07
• DOI: 10.1177/1066896919826708
• Languages: English
• ISSNs: 1066-8969

Abstract

Villous adenomas arising in the bladder following augmentation cystoplasty procedures are exceedingly rare. Even rarer is their occurrence in the native bladder mucosa and the upper urinary tract. In this article, we present a unique case of multifocal recurrent villous adenoma involving native bladder mucosa of an augmented bladder, bilateral ureters, and renal pelvis, with coexistent foci of adenocarcinoma and neuroendocrine carcinoma, in a patient with history of augmentation colocystoplasty. We additionally discuss the pathogenesis of development of carcinoma in the setting of augmentation cystoplasty.